You may have heard of Ozempic, Wegovy, Mounjaro. These semaglutides have been widely used to manage type 2 diabetes, aiding in blood sugar control and appetite suppression. While they offer some benefits, it’s important to be aware of the potential risks associated with their use:
- Hypoglycemia
One of the risks associated with semaglutides (Ozempic, Wegovy, Mounjaro) is the possibility of hypoglycemia, or low blood sugar. These medications work by increasing insulin release and reducing glucagon secretion, which can lead to blood sugar levels dropping too low. It’s essential for patients to monitor their blood sugar levels regularly and be cautious about other factors that can contribute to hypoglycemia, such as excessive exercise and skipping meals.
- Gastrointestinal Side Effects
The most common reported side effects are gastrointestinal when taking semaglutides (Ozempic, Wegovy, Mounjaro). These can include nausea, diarrhea, vomiting, constipation and abdominal discomfort. It’s important to consult with a healthcare provider if they persist or become severe.
- Pancreatitis
There have been rare reports of pancreatitis associated with the use of semaglutides. Pancreatitis is an inflammation of the pancreas and can be a serious condition. Patients should be vigilant and promptly report any signs or symptoms of pancreatitis, such as severe abdominal pain, to their healthcare provider.
- Thyroid C-Cell Tumors
In preclinical studies, GLP-1 RAs like Ozempic, Wegovy, Mounjaro and semaglutides have been associated with thyroid C-cell tumors in rodents. While there is limited evidence of this effect in humans, it is still a potential risk to consider. Patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 may need closer monitoring.
- Allergic Reactions
Allergic reactions to semaglutides (Ozempic, Wegovy, Mounjaro) can occur. Signs of an allergic reaction may include hives, itching, rash, swelling of the face or throat, severe dizziness, or difficulty breathing. If any of these symptoms occur, medical attention should be sought immediately.
- Other side effects
Other reported side effects may include bloating, burping, excessive gas, bad breath, hair loss, fatigue, dizziness, vision changes, depression. Immediately consult your healthcare provider if you experience any of these symptoms.
Semaglutides (Ozempic, Wegovy, Mounjaro) are valuable medications in the management of type 2 diabetes, providing improved blood sugar control. However, like all medications, they come with potential risks! It’s crucial for patients prescribed these drugs to be informed about these risks and work closely with their healthcare provider to monitor and manage any side effects. By doing so, patients can make informed decisions and achieve better outcomes in their diabetes management.
Dr. Vaziri highly recommends following a custom nutrition plan with weekly monitoring and guidance if you are using semaglutides (Ozempic, Wegovy, Mounjaro) for weight loss. This is critical for long term weight maintenance. The appetite suppression effects of semaglutides (Ozempic, Wegovy, Mounjaro) vanish once patients wean off the drugs and the weight will return without proper nutritional support.
